You can definitely print different materials on the same nozzle. However, you may experience extruding issue when you print PLA after other engineering materials such as ABS or PETG. The reason is that engineering materials usually require higher printing temperature than PLA. You will need to heat up the extruder to the temperature required by the previously used materials (e.g. 260C if ABS is previously used), then load PLA for a minute to two. Once PLA filament is loaded fine, you can lower the printing temperature to normal PLA range and enjoy printing.
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